Aurelien Tchouameni and Dayot Upamecano did not join in the France training on Monday.
This raises the possibility they might both miss the semi-final against Morocco.
France are gearing up for their second consecutive World Cup semi-final but have done so without two players who have played a key role in them getting this far.
Tchouameni smashed their opening goal against England beyond Jordan Pickford with Upamecano starting in all but one of their games thus far, the 1-0 loss to Tunisia in the group stage.
Should the pair not make the game and have to start on the bench, France would have little trouble replacing them.
Ibrahima Konate has shown he is more than capable on the international stage with the likes of Matteo Guendouzi and Jordan Veretout ready to step into the midfield if needed.
Deschamps would much rather his first choice men be available for the semi-final clash and they very well could be. Missing training could be for a number of reasons but it seems odd in the circumstance that the pair have missed a session two days shy of the semi-final.
