With few options at his disposal, Erik ten Hag makes just one change from the defeat to Brighton.
Scott McTominay drops to the bench, replaced by Facundo Pellistri.
Summer signings Rasmus Hojlund and Sergio Reguilon – both of whom impressed on their home debuts at the weekend – keep their places, as does Marcus Rashford.
The forward attempted nine shots against Brighton, his most ever in a single Premier League match, and the most by a Man Utd player without scoring in the competition since Zlatan Ibrahimovic against Burnley in October 2016 (12).
Bayern Munich team news
Team to face Man Utd: Ulreich, Laimer, Upamecano, Kim, Davies, Kimmich, Goretzka, Sane, Musiala, Gnabry, Kane
Manchester United team news
Team to play Bayern: Onana; Dalot, Lindelof, Martinez, Reguilon; Casemiro, Eriksen; Fernandes, Pellistri, Hojlund, Rashford
