Jurgen Klopp has also made six changes following Liverpool’s win over Union Saint-Gilloise on Thursday.
Matip, Van Dijk and Robertson all come into the back four, with Konate, Quansah and Tsimikas dropping out.
Mac Allister and Szoboszlai move into midfield as Endo and Gravenberch – who scored in midweek – are placed onto the bench.
Diaz returns in attack in place of the suspended Jota.
Roberto De Zerbi continues to chop and change his side amid Europa League demands, making six changes for the visit of Liverpool.
A change of shape looks as though it could be on the cards, with the Seagulls team full of attacking threat as Mitoma and March look to be lining up as wing-backs.
Adringa, Ferguson and Pedro all come into the attack, while Baleba starts in midfield, Igor moves into defence and Verbruggen is handed the goalkeeper jersey.
Steele, Van Hecke, Lamptey, Dahoud, Fati and Welbeck all drop out after starting the 2-2 draw in Marseille on Thursday.
Brighton team news
Team to play Liverpool: Verbruggen; Veltman, Dunk, Igor; March, Gross, Baleba, Mitoma; Adringa, Ferguson, Pedro.
Subs: Steele, Webster, Dahoud, Gilmour, Lallana, Welbeck, Van Hecke, Fati, Hinshelwood.
Liverpool team news
Team to play Brighton: Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Elliott, Mac Allister, Szoboszlai; Salah, Nunez, Diaz.
Subs: Adrian, Gomez, Endo, Konate, Tsimikas, Gravenberch, Chambers, Doak, Quansah.
