Jurgen Klopp has made six changes from the side that breezed past LASK in the Europa League on Thursday.
Alexander-Arnold, Matip and Van Dijk all return to the defence, with Gomez, Konate and Quansah dropping to the bench.
Mac Allister and Szoboszlai come into the midfield as Endo and Elliott take a place among the subs.
In attack, Nunez replaces Gakpo, who is on the bench.
Fulham have made three changes after beating Wolves on Monday.
Surprisingly, Willian – who scored twice in that victory – drops to the bench, with Wilson coming in to start against his former side.
Tete replaces Castagne at right-back, while Palhinha returns from suspension to take the place of captain Cairney in midfield.
Muniz, Traore and Diop all remain absent.
Liverpool team news
Team to play Fulham: Kelleher; Alexander-Arnold, Matip, Van Dijk, Tsimikas; Gravenberch, Mac Allister, Szoboszlai; Salah, Nunez, Diaz.
Subs: Adrian, Gomez, Endo, Konate, Jones, Gakpo, Elliott, Doak, Quansah.
Fulham team news
Team to play Liverpool: Leno; Tete, Bassey, Ream, Robinson; Reed, Palhinha; Wilson, Pereira, Iwobi; Jimenez.
Subs: Rodak, Adarabioyo, Cairney, Ballo-Toure, Decordova-Reid, Willian, Castagne, Lukic, Vinicius.
