Harry Maguire makes his first Premier League start since 13 August, while Cristiano Ronaldo is also in the Manchester United first XI.
Maguire comes in for the injured Raphael Varane as Ronaldo makes his first league start since 16 October. Meanwhile, winger Antony is not included in the Manchester United squad.
In total there are four changes for the hosts from the game against FC Sheriff, with Marcus Rashford, Luke Shaw and Anthony Elanga also starting.
West Ham make one change to the side that beat Bournemouth in their last Premier League game as Craig Dawson comes in for Ben Johnson, who drops to the bench.
Man Utd team news – Ronaldo starts
Team to face West Ham: De Gea, Shaw, Dalot, Maguire, Martinez, Casemiro, Eriksen, Fernandes, Elanga, Rashford, Ronaldo.
Subs: Bishop, Dubravka, Malacia, Fred, Sancho, Pellistri, Van de Beek, McTominay, Garnacho.
West Ham team news – Dawson returns
Team to face Man Utd: Fabianski, Cresswell, Kehrer, Zouma, Dawson, Rice, Soucek, Downes, Benrahma, Bowen, Scamacca.
Subs: Areola, Johnson, Coufal, Fornals, Antonio, Lanzini, Ogbonna, Coventry, Emerson.
Room for improvement
Erik ten Hag praised his team’s recent progress but stated that there is still a lot of “room for improvement.”
Manchester United are on a roll after a dismal start to life under Ten Hag. However, the Red Devils manager was quick to urge his players not to get too far ahead of themselves.
Speaking to Manutd.com, the Dutchman said: “We are doing well. You see we are developing. We are getting better game by game and that has to be. The process is in progress, eh, and there is still a lot of room for improvement.”
The Red Devils have not lost a match in their last seven appearances in all competitions since their 6-3 derby setback to Manchester City. Most recently, United defeated Sheriff 3-0 in the Europa League, a result that Ten Hag described as “very professional.”
