Ange Postecoglou understandably is largely sticking with the same Spurs team that drew 2-2 at Arsenal.
The only change is enforced, with the injured Brennan Johnson being replaced by Richarlison.
The other big news for Spurs is that James Maddison and Heung-min Son are deemed fit enough to start.
Liverpool have largely reverted to the side which beat West Ham in the Premier League last week, with Cody Gakpo – who was on the scoresheet against Leicester in the Carabao Cup in midweek – coming in for Darwin Nunez.
Fit-again Trent Alexander-Arnold is back in the matchday squad, beginning on the bench alongside Diogo Jota and Ryan Gravenberch.
Liverpool team news
Team to play Tottenham: Alisson; Gomez, Matip, Van Dijk, Robertson; Mac Allister, Jones, Szoboszlai; Salah, Gakpo, Diaz.
Subs: Kelleher, Endo, Konate, Nunez, Elliott, Jota, Tsimikas, Gravenberch, Alexander-Arnold.
Spurs team news
Team to face Liverpool: Vicario; Porro, Romero, Van de Ven, Udogie; Sarr, Bissouma; Kulusevski, Maddison, Son; Richarlison.
Subs: Forster, Skipp, Hojbjerg, Royal, Solomon, Davies, Phillips, Veliz, Donley.
