Tottenham make three changes to the side that narrowly beat Burnley last weekend.
Radu Dragusin, Rodrigo Bentancur and Pierre-Emile Hojbjerg all come into the side, with Oliver Skipp and Dejan Kulusevski dropping to the bench.
Yves Bissouma is out with a knee injury.
Tottenham XI: Vicario; Porro, Romero, Dragusin, Van de Ven; Sarr, Bentancur, Hojberg; Johnson, Son, Maddison.
Subs: Austin, Skipp, Gil, Royal, Lo Celso, Kulusevski, Scarlett, Moore, Hall.
Manchester City make just one change to the team that thrashed Fulham last time out.
Captain Kyle Walker starts with Nathan Ake dropping to the bench.
Man City XI: Ederson; Akanji, Walker, Dias, Gvardiol; Rodri, Kovacic; Silva, De Bruyne, Foden; Haaland.
Subs: Ortega, Stones, Ake, Grealish, Doku, Alvarez, Nunes, Bobb, Lewis.
